The Institute of Molecular Biochemistry (IMB) is always open for BSc, MSc, PhD and postdoctoral candidates who are approaching us proactively and wish to pursue a project fitting to our research portfolio. In this case, please get directly in touch with the leader of the group you are interested in.
In addition, we currently have the following vacancies:
4-year PostDoc Position in the Teis Lab:
Nutrient transporter regulation by ubiquitin ligase complexes: We are looking for a PostDoc who wants to understand how human cells use a-arrestin ubiquitin ligase complexes to selectively adjust their nutrient transporter repertoire when they enter and exit quiescence. The key questions of this research project are: (1) How do a-arrestins work together with ubiquitin ligases to target nutrient transports for degradation? (2) How are a-arrestins controlled? (3) How does the a-arrestin mediated downregulation of nutrient transports curb cell growth and how does it help to stablish quiescence? These are significant processes since Loss of function mutations in one a-arrestin cause defects in the selective lysosomal degradation of an essential amino acid transporter, and are linked with a novel rare metabolic disease.
If you find these questions interesting, please contact david.teis@i-med.ac.at
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4-year PostDoc Position in the Teis Lab:
Golgi protein quality control: We are looking for a PostDoc who wants to understand how protein quality control at the Golgi maintain the cellular membrane protein and lipid composition.
The key questions are: (1) How does the Golgi quality control network prevent the spreading of orphaned proteins across the secretory and endo-lysosomal pathway. (2) Identify the most important players in Golgi quality control in human cells and their substrates. (3) Delineate how Golgi protein quality control is embedded in the cellular protein homeostasis system.
If you find these questions interesting, please contact david.teis@i-med.ac.at